India is home to 115 million adolescent girls aged 10– 19 years; 56 per cent adolescent girls are anaemic. Anaemia limits girls‟ growth and learning ability, increases their vulnerability to school dropout, reduces productivity and earnings later in life and increases the risk of maternal death and newborn low birth weight both in early wed adolescent girls and when girls become adult women. Recognizing the consequences of anaemia for adolescent girls, Government of India‟s Ministries of Education, Women and Child Development, and Health are scaling up with UNICEF technical support, a programme for the control of anaemia in adolescent girls. The objective of the programme is to reduce the prevalence and severity of anaemia in school-going adolescent girls using schools as delivery channel and in out-of-school adolescent girls using community-based Anganwadi Centers as the delivery platform. The programme comprises three essential interventions: 1) weekly iron folic acid (IFA) supplementation (100 mg elemental iron + 0.5 mg of folic acid) for 52 weeks in a year to prevent IFA deficiency; 2) biannual deworming (albendazole 400 mg) to prevent helminth infestations; and 3) information, counselling and support on how to improve dietary intake and prevent anaemia. The evaluation of the initial phase programmes showed an average 20% reduction in the prevalence of anaemia after 1-2 years of implementation. Currently UNICEF focuses on the technical support to build the capacity of programme managers and supervisors, the development of programme communication strategies and tools for girls, families, and communities, and the design of monitoring systems and tools to assess programme performance and quality.